| Clinical Approches to Post- COVID-19 OLFACTORY Nerve DYSFUNCTION: A Systematic Review of Randomized Controlled Trials. |
| Paper ID : 1034-ISCSR3 (R1) |
| Authors |
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Sohaila Ahmed Galal *1, Doaa Saeed Mohamed2, Doha Hamed Moustafa3 1Student at Badr University in Cairo , Egypt 2Lecturer, Department of Physical therapy for Woman’s Health, Faculty of Physical Therapy, Badr University in Cairo, Cairo, Egypt 3Lecturer ,Basic Sciences Department, Faculty of Physical Therapy, Badr University in Cairo, Egypt |
| Abstract |
| The COVID-19 is a pandemic issue which highlighted number of illnesses in humans that affect hepatic, digestive , respiratory and neurological systems to varying degrees of severity . fever , cough , headache, myalgia or joint discomfort ,Gustatory dysfunction(GD), diarrhea ,sore throat are common clinical signs of of covid 19 and a unique early prevalent sign which is Olfactory dysfunction (OD) : OD also known as anosmia, hyposmia or dysosmia which affecting up to 50% of infected individuals. This systematic review aims to explore clinical approaches for managing post-COVID-19 olfactory nerve dysfunction .Methods : a systematic review of Randomized controlled trials from Pubmed , Google Scholar , Cochrane , MEDLINE , Scopus , EmBase to find clinical approaches to post covid Olfactory dysfunction (OD ) which Conducted from 2020 to 2024. Results : A total of 219 records were initially identified. After selection of titles and abstracts, 28 were retrieved for full-text analysis. 21 Studies matched our inclusion criteria and were included for the qualitative synthesis . Various interventions were analyzed, including olfactory training, platelet-rich plasma (PRP) injections, and corticosteroid therapies, to assess their impact on olfactory recovery and quality of life. Conclusion : The results suggest that PRP may promote nerve regeneration, while olfactory training offers a safe, cost-effective first-line treatment. Conversely, topical corticosteroids showed limited long-term benefits. The review underscores the need for standardized treatment protocols and long-term studies to refine therapeutic strategies. These findings provide valuable insights for clinicians and researchers working to improve post-viral recovery pathways for patients experiencing persistent olfactory dysfunction. |
| Keywords |
| Keywords: COVID-19, Olfactory Dysfunction, Post-viral Anosmia, Platelet-Rich Plasma, Olfactory Training, Corticosteroids |
| Status: Abstract Accepted |