The efficacy of transcranial magnetic stimulation on overactive bladder: A systematic review |
Paper ID : 1035-ISCSR3 (R1) |
Authors |
Muhammad Hosny Muhammad Arafa Ibrahim *1, Nada A Salah2, Merna amr saber3, Nancy Mahmoud Ahmed4, Mohamed Hamed Eid5, Rodaina Mohamed Saifeldeen6, Reda Hesham1, Omnia Mohamed Abd El Moneim7, Mona Salah Zahran1, Yasmeen Moftah8, Doaa Abd Elhalem Elsaidi9, Abdelrahman Sameh A Attia10 1Fifth year student, Faculty of Physical Therapy, Benha University 2Fourth year student, faculty of physical Therapy, Benha University 3Fourth year student Faculty of physical therapy, benha university 4Fourth year student, Faculty of Phhsical Therapy Benha University 5Fourth year srudent, Faculty of physical therapy benha university 6Fourth year student, Faculty of Physical Therapy, Benha University 7Demonstrator at basic science department, faculty of physical therapy, Benha University. 8Fifth year student faulty of Physical Therapy Benha University 9Second year student, Faculty Of Physical Therapy, Benha University 10Fifth year student Faculty of Physical Therapy Benha University |
Abstract |
Background: Overactive bladder is a condition that totally affects the patient's lifestyle, as there is always a strong desire to urinate multiple times a day, even though the bladder isn’t full. Stroke, spinal cord injury, and multiple sclerosis are key factors leading to overactive bladder. Theories such as neurogenic, myogenic, and afferent signaling explain this, with reduced inhibition of the micturition reflex post-cerebrovascular accident being a primary cause. Objective: to synthesize the effects of Transcranial Magnetic Stimulation (TMS) on Overactive Bladder (OAB) symptoms Methods: the included databases were PubMed, Scopus, Web of Science, and Cochrane Library. All included studies were only English randomized control trials (RCTs) from 2018 to 2024.We included RCTs examining the effect of TMS compared with other traditional rehabilitation programs on OAB. We excluded non randomized trials, case reports, and narrative reviews. Risk of bias assessed with the ROB2. A systematic review was conducted using the Preferred Reporting Items for Systematic and Meta-Analyses (PRISMA) guidelines. The review was registered in PROSPERO (CRD42025633762). Results: Out of 148 articles were identified, only 4 randomized controlled trials met inclusion criteria. The selected studies included a total of 210 participants. Significant improvement has been noticed in urodynamic parameters (maximum cystometric capacity, maximum detrusor pressure, and residual urine volume) in TMS group in three studies. Significant improvement has been noticed in overactive bladder symptom score (OABSS) in two studies. Significant improvement has been noticed in Incontinence Quality-of-Life Questionnaire (I-QOL), International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF), and pelvic floor surface electromyography in one study. Conclusions: urodynamic parameter changes and patient-reported outcomes indicate that transcranial magnetic stimulation (TMS) has a considerable potential to alleviate overactive bladder (OAB) symptoms. To validate these results and prove long-term efficacy, further extensive, high-caliber research is necessary. |
Keywords |
Transcranial Magnetic Stimulation , TMS , Overactive Bladder , Urinary Incontinence . |
Status: Abstract Accepted |